The hypotensive effect of activated apelin receptor is correlated with β-arrestin recruitment. Besserer-Offroy É, Bérubé P, Côté J, Murza A, Longpré JM, Dumaine R, Lesur O, Auger-Messier M, Leduc R, Marsault É, Sarret P. Pharmacol Res. 2018 Mar 9. 10.1016/j.phrs.2018.02.032
In search of the optimal macrocyclization site for neurotensin. Sousbie M, Besserer-Offroy É, Longpré JM, Leduc R, Sarret P, Marsault É. ACS Med Chem Lett. 2018 Jan 29. doi: 10.1021/acsmedchemlett.7b00500
I won the first prize for my publication ‘Signaling signature of neurotensin receptor type 1 with endogenous ligands‘ published earlier this year in European Journal of Pharmacology. This publication prize is awarded by the Sherbrooke Neuroscience Centre.
My abstract, “Phosphomimetic lipopeptides as new tools to investigate β-arrestin-mediated functions.” has been selected for a 15-min. short talk at the 2017 edition of the Great Lakes GPCR Retreat which will be held in Ottawa on Oct. 19-21, 2017.
I received Dean’s honour list for my outstanding work all along 2016. This award is reserved for the top 10% of graduate students at the Faculty of medicine.
Use of Molecular Modeling to Design Selective-NTS2 Neurotensin Analogues. Fanelli R, Floquet N, Besserer-Offroy É, Delort B, Vivancos M, Longpré JM, Renault P, Martinez J, Sarret P, Cavelier F. J Med Chem. 2017 Apr 3. doi: 10.1021/acs.jmedchem.6b01848
Signaling signature of neurotensin receptor type 1 with endogenous ligands. Besserer-Offroy É, Brouillette RL, Lavenus S, Froehlich U, Brumwell A, Murza A, Longpré JM, Marsault É, Grandbois M, Sarret P, Leduc R. Eur J Pharmacol. 2017 Mar 21. doi: 10.1016/j.ejphar.2017.03.046
Structure-activity relationship of novel macrocyclic biased apelin receptor agonists. Murza A, Sainsily X, Côté J, Bruneau-Cossette L, Besserer-Offroy É, Longpré JM, Leduc R, Dumaine R, Lesur O, Auger-Messier M, Sarret P, Marsault É. Org Biomol Chem. 2016 Dec 7. PMID: 27924341
I have been selected for a talk at Journée Phare 2016 and my presentation “Phosphomimetic lipopeptides as new tools to investigate β-arrestin-mediated functions.” won the second best oral presentation !
Design, Synthesis, and Biological Evaluation of Novel CXCR4 Inverse Agonists Mona CE, Besserer-Offroy É, Cabana J, Leduc R, Lavigne P, Heveker N, Marsault E, Escher E Org Biomol Chem. 2016 Oct 04. DOI: 10.1039/C6OB01484D