Manuscript accepted in Biochemical Pharmacology

Angiotensin II cyclic analogs as tools to investigate AT1R biased signaling mechanisms. St-Pierre D, Cabana J, Holleran BJ, Besserer-Offroy É, Escher E, Guillemette G, Lavigne P, Leduc R. Biochem Pharmacol. 2018 Apr 20. 10.1016/j.bcp.2018.04.021

Manuscript accepted in Pharmacological Research

The hypotensive effect of activated apelin receptor is correlated with β-arrestin recruitment. Besserer-Offroy É, Bérubé P, Côté J, Murza A, Longpré JM, Dumaine R, Lesur O, Auger-Messier M, Leduc R, Marsault É, Sarret P. Pharmacol Res. 2018 Mar 9. 10.1016/j.phrs.2018.02.032

Manuscript accepted in the Journal of Medicinal Chemistry

Use of Molecular Modeling to Design Selective-NTS2 Neurotensin Analogues. Fanelli R, Floquet N, Besserer-Offroy É, Delort B, Vivancos M, Longpré JM, Renault P, Martinez J, Sarret P, Cavelier F. J Med Chem. 2017 Apr 3. doi: 10.1021/acs.jmedchem.6b01848

Manuscript accepted in European Journal of Pharmacology

Signaling signature of neurotensin receptor type 1 with endogenous ligands. Besserer-Offroy É, Brouillette RL, Lavenus S, Froehlich U, Brumwell A, Murza A, Longpré JM, Marsault É, Grandbois M, Sarret P, Leduc R. Eur J Pharmacol. 2017 Mar 21. doi: 10.1016/j.ejphar.2017.03.046

New manuscript accepted in Organic and Biomolecular Chemistry

Structure-activity relationship of novel macrocyclic biased apelin receptor agonists. Murza A, Sainsily X, Côté J, Bruneau-Cossette L, Besserer-Offroy É, Longpré JM, Leduc R, Dumaine R, Lesur O, Auger-Messier M, Sarret P, Marsault É. Org Biomol Chem. 2016 Dec 7. PMID: 27924341

Manuscript accepted in the Journal of Medicinal Chemistry

Structure Activity Relationship and Signaling of New Chimeric CXCR4 Agonists. Mona CE, Besserer-Offroy É, Cabana J, Lefrançois M, Boulais PE, Lefebvre MR, Leduc R, Lavigne P, Heveker N, Marsault E, Escher E. J Med Chem. 2016 Jul 19. PMID: 27434274

Manuscript accepted in ACS Chemical Neuroscience

Identification of 2-({[1-(4-fluorophenyl)-5-(2-methoxyphenyl)-1H-pyrazol-3-yl]carbonyl}amino)tricyclo[3.3.1.13,7]decane-2-carboxylic acid (NTRC-844) as a selec-tive antagonist for the Rat Neurotensin recep-tor type 2. Thomas JB, Vivancos M, Giddings AM, Wiethe RW, Warner KR, Murza A, Besserer-Offroy É, Longpre JM, Runyon SP, Decker AM, Gilmour BP, Sarret P. ACS Chem Neurosci. 2016 Jun 30. PMID: 27359371

Manuscript accepted in the Journal of Medicinal Chemistry

Discovery and structure-activity relationship of a bioactive fragment of ELABELA that modulates vascular and cardiac functions. Murza A, Sainsily X, Coquerel D, Côté J, Marx P, Besserer-Offroy É, Longpre JM, Lainé J, Reversade B, Salvail D, Leduc R, Dumaine R, Lesur O, Auger-Messier M, Sarret P, Marsault E. J Med Chem. 2016 Mar 17. PMID: […]